A Simple Key For pharmaceutical APIs and their source Unveiled
A Simple Key For pharmaceutical APIs and their source Unveiled
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Daunorubicin interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. This inhibits the development of your enzyme topoisomerase II, which relaxes supercoils in DNA for transcription.
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Epirubicin is favoured about doxorubicin, the most well-liked anthracycline, in a few chemotherapy regimens because it appears to trigger fewer Negative effects. In 1999 epirubicin obtained FDA approval to be a ingredient of adjuvant therapy in node-beneficial clients.